Plasmid-mediated tetracycline resistance in Haemophilus ducreyi.
نویسندگان
چکیده
Clinical isolates of Haemophilus ducreyi were shown to be resistant to tetracycline. Resistance was associated in some strains with a 30-megadalton plasmid capable of transferring resistance in conjugative matings with other strains of H. ducreyi and other species of Haemophilus. Restriction endonuclease digestion patterns suggest a relationship between H. ducreyi plasmids and other tetracycline resistance plasmids in Haemophilus. The presence of plasmid-mediated resistance to the tetracyclines limits the use of these agents for the treatment of chancroid.
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عنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 25 2 شماره
صفحات -
تاریخ انتشار 1984